The COMET tool rapidly classifies HIV-1 nucleotide sequences into subtypes. You can submit your sequences either by pasting them in the form (b) or uploading them (a).
|1.0||smaller HIV-1 recombination detection window (should detect more URF), CRF additions to the training set||2014-03-26|
|0.5||new HIV-1 thresholds, should slightly improve the results||2012-06-11|
|0.3||additional support for CRF 44_BF - 49_cpx for HIV-1||2011-12-20|
(a) upload the sequences in fasta format:
(b) paste the sequences in fasta format (try out example):
The submitted sequences are deleted as soon the results have been generated.
HIV-1 training set
Publications that used COMET:
Pineda-Peña AC, Faria NR, Imbrechts S, Libin P, Abecasis AB, Deforche K, Gómez-López A, Camacho RJ, de Oliveira T, Vandamme. Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: Performance evaluation of the new REGA version 3 and seven other tools. Infect Genet Evol. 2013 May 7. pii: S1567-1348(13)00181-0. doi: 10.1016/j.meegid.2013.04.032. (full text)
Lessells RJ, Katzenstein DK, de Oliveira T. Are subtype differences important in HIV drug resistance? Curr Opin Virol. 2012 Oct;2(5):636-43. doi: 10.1016/j.coviro.2012.08.006. Epub 2012 Sep 21.
(*) The COMET-HIV and COMET-HCV services provided herein are "For non-commercial research use only". For all commercial uses, please contact our Exclusive Licensee, ABL SA (www.ablsa.com) at email@example.com.
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